Publicacions recents

Nanostructured Toxins for the Selective Destruction of Drug-Resistant Human CXCR4 + Colorectal Cancer Stem Cells. Naroa Serna, Patricia Álamo, Prashanthi Ramesh, Daria Vinokurova, Laura Sánchez-García, Ugutz Unzueta, Alberto Gallardo, María Virtudes Céspedes, Esther Vázquez, Antonio Villaverde, Ramón Mangues, Jan Paul Medema. J Control Release. 2020 Apr 10;320:96-104. Epub 2020 Jan 10.

 

A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models. Aïda Falgàs, Victor Pallarès, Ugutz Unzueta, María Virtudes Céspedes, Irene Arroyo-Solera, María José Moreno, Jorge Sierra, Alberto Gallardo, María Antonia Mangues, Esther Vázquez , Antonio Villaverde, Ramon Mangues, Isolda Casanova. Haematologica. 2020 Mar;105(3):741-753. Epub 2019 Jun 27.

 

Engineering a Nanostructured Nucleolin-Binding Peptide for Intracellular Drug Delivery in Triple-Negative Breast Cancer Stem Cells. Mireia Pesarrodona, Laura Sánchez-García, Joaquin Seras-Franzoso, Alejandro Sánchez-Chardi, Ricardo Baltá-Foix, Patricia Cámara-Sánchez, Petra Gener, José Juan Jara, Daniel Pulido, Naroa Serna, Simó Schwartz Jr, Miriam Royo, Antonio Villaverde, Ibane Abasolo, Esther Vazquez. ACS Appl Mater Interfaces. 2020 Feb 5;12(5):5381-5388. Epub 2020 Jan 21.

 

Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci. María Virtudes Céspedes, Olivia Cano-Garrido, Patricia Álamo, Rita Sala, Alberto Gallardo, Naroa Serna, Aïda Falgàs, Eric Voltà-Durán, Isolda Casanova, Alejandro Sánchez-Chardi, Hèctor López-Laguna, Laura Sánchez-García, Julieta M Sánchez, Ugutz Unzueta, Esther Vázquez, Ramón Mangues, Antonio Villaverde. Adv. Mater. 2020 Feb;32(7). Epub 2019 Dec 27.

 

Self-assembling as regular nanoparticles dramatically minimizes photobleaching of tumour-targeted GFP. Ugutz Unzueta, Mònica Roldán, Mireia Pesarrodona , Raul Benitez, Alejandro Sánchez-Chardi, Oscar Conchillo-Solé, Ramón Mangues, Antonio Villaverde, Esther Vázquez. Acta Biomater. 2020 Feb;103:272-280. Epub 2019 Dec 6.

 

Nanostructure Empowers Active Tumor Targeting in Ligand‐Based Molecular Delivery.. Hèctor López-Laguna, Rita Sala, Julieta M. Sánchez, Patricia Álamo, Ugutz Unzueta, Alejandro Sánchez-Chardi, Naroa Serna, Laura Sánchez-García, Eric Voltà-Durán, Ramón Mangues, Antonio Villaverde and Esther Vázquez. Part. Syst. Charact.  2019 Nov; 36(11). Epub 2019 Oct 16.

 

Collaborative membrane activity and receptor-dependent tumor cell targeting for precise nanoparticle delivery in CXCR4+ colorectal càncer. Rita Sala, Laura Sánchez-García, Naroa Serna, María Virtudes Céspedes, Isolda Casanova, Mònica Roldán, Alejandro Sánchez-Chardi, Ugutz Unzueta, Esther Vázquez, Ramón Mangues, Antonio Villaverde. Acta Biomater.  2019 Nov;99:426-432. Epub 2019 Sep 5.

 

Protein-driven Nanomedicines in Oncotherapy. Isolda Casanova, Ugutz Unzueta, Irene Arroyo-Solera, Maria Virtudes Céspedes, Antonio Villaverde, Ramon Mangues, Esther Vazquez. Curr. Opin. Pharmacol. 2019 Aug; 47:1-7. Epub 2019 Jan 25. 

 

Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies. Mireia Pesarrodona, Toni Jauset, Zamira V Díaz-Riascos, Alejandro Sánchez-Chardi, Marie-Eve Beaulieu, Joaquin Seras-Franzoso, Laura Sánchez-García, Ricardo Baltà-Foix, Sandra Mancilla, Yolanda Fernández, Ursula Rinas, Simó Schwartz Jr, Laura Soucek, Antonio Villaverde, Ibane Abasolo , Esther Vázquez. Adv Sci (Weinh). 2019 Jul 24;6(18):1900849.  Epub 2019 Sep 18.

 

Latest Advances in the Development of Eukaryotic Vaults as Targeted Drug Delivery Systems. Amanda Muñoz-Juan, Aida Carreño, Rosa Mendoza, José L Corchero. Pharmaceutics. 2019 Jun 28;11(7):300.

 

Efficient bioactive oligonucleotide-protein conjugation for cell-targeted cancer therapy. Anna Aviñó , Ugutz Unzueta, María Virtudes Céspedes, Isolda Casanova, Esther Vázquez, Antonio Villaverde, Ramon Mangues , Ramon Eritja. ChemistryOpen. 2019 Mar 28;8(3):382-387. Epub 2019 Mar.

 

Recruiting potent membrane penetrability in tumor cell-targeted protein-only nanoparticles. Naroa Serna, Julieta M Sánchez, Ugutz Unzueta, Laura Sánchez-García, Alejandro Sánchez Chardi, Ramón Mangues, Esther Vázquez and Antonio Villaverde. Nanotechnolology. 2019 Mar 15;30(11):11510 Epub 2018 Dec 18.

 

Assembly of histidine-rich protein materials controlled through divalent cations. Hèctor López-Laguna  , Ugutz Unzueta, Oscar Conchillo-Solé, Alejandro Sánchez-Chardi, Mireia Pesarrodona, Olivia Cano-Garrido, Eric Voltà, Laura Sánchez-García, Naroa Serna, Paolo Saccardo, Ramón Mangues, Antonio Villaverde, Esther Vázquez. Acta Biomater. 2019 Jan 1;83:257-264. Epub 2018 Oct 24.

 

Bacterial inclusion bodies are industrially exploitable amyloids. Ario de Marco, Neus Ferrer-Miralles, Elena Garcia-Fruitós, Anna Mitraki, Spela Peternel , Ursula Rinas, Mauricio A Trujillo-Roldán, Norma A Valdez-Cruz, Esther Vázquez, Antonio Villaverde. FEMS Microbiol. Rev. 2019 Jan 1;43(1):53-72. Epub 2018 Oct 24.

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